A team of researchers at Ecole Polytechnique Fédérale de Lausanne explored how age and sex influence our body clocks. The study is published in the journal Science.
The researchers used a data-science algorithm to create a comprehensive whole-organism view of 24-hour gene expression rhythms in 46 human tissues.
The results revealed that age and sex influence our body clocks. Sex- and age- specific gene expression rhythms spread across the body generally get reduced with age. These gene expression rhythms are also influenced by factors like metabolism, stress response pathways, and immunity.
The authors added: “This study provides new insights into the complex interplay between our body clock, sex, and age. By understanding these rhythms, we might find new ways of diagnosing and treating pathologies such as sleep disorders and metabolic diseases.”
To Know More You May Refer To
Talamanca, L., Gobet, C., & Naef, F. (2023). Sex-dimorphic and age-dependent organization of 24-hour gene expression rhythms in humans. Science (New York, N.Y.), 379(6631), 478–483. https://doi.org/10.1126/science.add0846